From the Small Business Administration comes statistics about small businesses (PDF) from the years 2001-2004.  Overall, Small Businesses (firms with less than 500 employees):

• Represent 99.7% of all Employer Firms.
• Employ half of all private sector employees.
• Have generated 60-80% of all new jobs annually over the last decade.
• Create more than 50% of nonfarm GDP.
• Produce 13 to 14 times more patents per employees than large firms.
• Employ 41% of high tech workers.
• 53% home-based and 3% franchises.

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